FUNDED COMPONENTS AND INVESTIGATORS OF
THE PROTEIN STRUCTURE INITIATIVE (PHASE 2)
Large-scale Centers PSI-2
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 Joint Center for Structural Genomics (JCSG)

Joint PSI-2 Activities (70%); Community Nominated Targerst (15%);
Biomedical Theme:  Proteins conserved in all kingdoms of life (15%)

  Ian Wilson
Kurt Wuthrich
Scott Lesley
Keith Hodgson
Adam Godzik
John Wooley
The Scripps Research Institute
The Scripps Research Institute
Genomics Institute of the Novartis Research Foundation _________________
Stanford Synchrotron Radiation Laboratory,
Burnham Institute
University of California at San Diego
 

Midwest Center for Structural Genomics (MCSG)

Joint PSI-2 Activities (70%); Community Nominated Targerst (15%);
Biomedical Theme: Pathogenic bacteria (15%)

  Andrzej Joachimiak
Janet Thornton
Wayne Anderson
David Fremont
Christine Orengo
Wladek Minor
Zbyszek Otwinowski
Aled Edwards
Argonne National Laboratory
European Bioinformatics Institute
Northwestern University
Washington University
University College London
University of Virginia
University of Texas-Southwestern Medical Center
University of Toronto
 

Northeast Structural Genomics Consortium (NESGC)

Joint PSI-2 Activities (70%); Community Nominated Targerst (15%);
Biomedical Theme: Networks of proteins in developmental biology and cancer (15%)

  Gaetano Montelione
Stephen Anderson
Wayne Hendrickson
Barry Honig
Diana Murray 
Burkhard Rost
Liang Tong   
John Hunt 
Andrew Laine  
Peter Allen
George De Titta
Cheryl Arrowsmith 
Masaori Inouye
Nancy Woychik
Michael Kennedy  
Thomas Szyperski
James Prestegard
Mark Gerstein
Rutgers University
Rutgers University
Columbia University
Columbia University
Columbia University
Columbia University
Columbia University
Columbia University
Columbia University
Columbia University
Hauptman Woodward Medical Research Institute
Ontario Cancer Institute at the University of Toronto
UMD-New Jersey
UMD-New Jersey
Miami University of Ohio
SUNY, Buffalo
University of Georgia
Yale University
 

New York Structural GenomiX Research Consortium (NYSGX)

Joint PSI-2 Activities (70%); Community Nominated Targerst (15%);
Biomedical Theme: Protein phosphatases and kinases (15%)

  Stephen K. Burley
Steve Almo  
S. Swaminathan
Mark Chance
Andras Fiser
Andrej Sali
Jeffrey Bonanno
SGX Pharmaceuticals, Inc.
Albert Einstein College of Medicine
Brookhaven National Laboratory
Case Western Reserve University
Columbia University
University of California at San Francisco
New York Structural Biology Center
     
 PSI-2 Specialized Centers
 

Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)

Specilizations: Whole gene synthesis, micro-capillaries, CLS

  Lance Stewart
Raymond Stevens
Peter Kuhn
Rustem Ismagilov
Ron Ruth
deCODE Biostructures
Scripps Research Institute
Scripps Research Institute
University of Chicago
Lyncean Technologies, Inc.
  Center for Eukaryotic Structural Genomics (CESG)

Specializations:  Eukaryote genomes, cell-free protein production

  John Markley
Brian Fox
George Phillips
Brian Volkman
Yaeta Endo
University of Wisconsin, Madison
University of Wisconsin, Madison
University of Wisconsin, Madison
Medical College of Wisconsin
CellFree Sciences, Ltd.
 

Center for High-Throughput Structural Biology (CHTSB)

Specializations: Expression and crystallization, esp. membrane proteins and complexes

  George De Titta
Eric Phizicky
Mark Dumont 
Sol Gruner
Mike Soltis 
Keith Hodgson
Igor Jurisica 
Alexander McPherson
Hauptman-Woodward Medical Research Institute
University of Rochester
University of Rochester
Cornell University
Stanford Synchrotron Radiation lab
Stanford Synchrotron Radiation Lab
University of Toronto
University of California, Irvine
 

Center for Structures of Membrane Proteins (CSMP)

Specialization:  Structures of membrane proteins

  Robert Stroud
Andrej Sali
Kathleen Giacomini 
Daniel Minor 
Senyon Choe
Roland Riek
Witold Kwiatkowski
James Holton
Ronald Kaback 
Henning Stahlberg 
University of California, San Francisco
University of California, San Francisco
University of California, San Francisco
University of California, San Francisco
Salk Institute
Salk Institute
Salk Institute
Advanced Light Source, Lawrence Berkeley National Laboratory
niversity of California, Los Angeles
University of California, Davis
 

Integrated Center for Structure and Function Innovation (ICSFI)

Specializations:  Modifying proteins for solubility and crystallization, esp. for complexes and membrane proteins

  Thomas Terwilliger
Anthony Kossiakoff
Shohei Koide
Valentina Terechko 
Zygmunt Derewenda
David Eisenberg   
Li-Wei Hung 
Los Alamos National Laboratory
University of Chicago
University of Chicago
University of Chicago
University of Virginia
University of California, Los Angeles
Lawrence Berkeley National Laboratory
 

New York Consortium on Membrane Protein Structure (NYCMPS)

Specialization:  Structures of membrane proteins  

  Wayne Hendrickson
Barry Honig 
John Hunt 
Ann McDermott
Burkhard Rost
Larry Shapiro 
Ming Zho
Mark Girvin
Da-Neng Wang 
Eric Gouaux 
Gaetano Montelione
Rod Mackinnon 
Thomas Szyperski
Masayori Inouye 
Nancy Woychik 
New York Structural Biology Center& Columbia University
Columbia University
Columbia University
Columbia University
Columbia University
Columbia University
Columbia University
Albert Einstein College of Medicine
New York University
Oregon Health and Science University
Rutgers University
Rockefeller University
SUNY-Buffalo
UMD-New Jersey
UMD-New Jersey
     
PSI-2 Homology Modeling Centers
 

New Methods for High-Resolution Comparative Modeling

Comparative modeling in a wide sequence identity range

  Roland Dunbrack
David Baker 
P Tseng 
Martin Tompa
Michael Jordan 
Jay Ponder 
Fox Chase Cancer Center
University of Washington
University of Washington
University of Washington
University of California, Berkeley
Washington University
 

Joint Center for Protein Modeling

Comparative modeling of remote homologs

  Adam Godzik
Piotr Cieplak
Yuzhen Ye 
Pavel Pevzner  
The Burnham Institute
The Burnham Institute
The Burnham Institute
University of California, San Diego
   PSI-2 Materials Repository
  Joshua LaBaer
Catherine Cormie
Andreas Rolfs
Harvard University
Harvard University
Harvard University
   Structural Genomics KnowledgeBase Center
  Helen Berman
Torsten Schwede
Paul Adams 
Wladek Mino
Rutgers University
University of Basel
Lawrence Berkeley Laboratory
University of Virginia